Bontkes, H.J.

Senior Scientist Immunology (Oral Cell Biology and Functional Anatomy)

Expertise

  • Cellular Immunology
  • Mucosal Immunology
  • Medical Immunology

Professional interests

  • Mechanisms and diagnosis of (metal) allergies
  • Mucosal immunity/tolerance
  • Immunomonitoring in cancer, celiac disease and rheumatoid arthritis

Professional employment history

 YearOccupation
 2016-present Senior Scientist Immunology, Oral Cell Biology
 2013-2015 Medical Immunologist, Dept Pathology, VU medical Center, Amsterdam
 2011-2013 Fellow Medical Immunology, Dept Pathology, VU medical Center, Amsterdam
 2008-2011 Research associate, Dept.  Hematology, VU medical Center, Amsterdam
 2005-2008 Research associate, Dept.  Pathology, VU medical Center, Amsterdam
 2004 Head Quality Control, Exp. Oncopathology, VU medical Center, Amsterdam
 1999-2005 Postdoc, Dept.  Pathology, VU medical Center, Amsterdam
 1999 PhD in Immunology
 1993 MSc in Immunology 

Selected scientific publications


Lübbers J, Vosslamber S, van de Stadt LA, van Beers-Tas M, Wesseling JG, von Blomberg BM, Witte BI, Bontkes HJ, van Schaardenburg D, Verweij CL. B cell signature contributes to the prediction of RA development in patients with arthralgia. Ann Rheum Dis. 2015 Sep;74(9):1786-8. doi: 10.1136/annrheumdis-2015-207324.
Ruben JM, Bontkes HJ, Westers TM, Hooijberg E, Ossenkoppele GJ, van de Loosdrecht AA, de Gruijl TD. In situ loading of skin dendritic cells with apoptotic bleb-derived antigens for the induction of tumor-directed immunity. Oncoimmunology. 2014 Jul 3;3(7):e946360. eCollection 2014.
Rachmawati D, Bontkes HJ, Verstege MI, Muris J, von Blomberg BM, Scheper RJ, van Hoogstraten IM. Transition metal sensing by Toll-like receptor-4: next to nickel, cobalt and palladium are potent human dendritic cell stimulators. Contact Dermatitis. 2013; 68:331-8.
Gross S, van Wanrooij RL, Nijeboer P, Gelderman KA, Cillessen SA, Meijer GA, Mulder CJ, Bouma G, von Blomberg BM, Bontkes HJ. Differential IL-13 production by small intestinal leukocytes in active coeliac disease versus refractory celiac disease. Mediators Inflamm. 2013; 2013:939047.
Moreno M, Molling JW, von Mensdorff-Pouilly, Verheijen RHM, Hooiberg E, Kramer D Reurs AW, van den Eertwegh AJM, von Blomberg BME, Scheper RJ, Bontkes HJ. Interferon-γ producing human invariant Natural Killer T-cells promote tumor associated antigen-specific cytotoxic T cell responses, J Immunol, 2008; 181:2446-2454.

LIST OF PUBLICATIONS (from 1999 until now)