Loon, J.J.W.A. van

+31 20 59 80871
acta ( mondgezondh )
Other staff member (Oral Cell Biology)


  • Space flight
  • General Gravitational Research (General)
  • Bone

Professional interests

  • Gravitational life and physical sciences
  • Cell mechanosensing
  • Connective tissue

Professional employment history

2009-2012Initiator / scientific / operation support in framework of collaborative initiative between the European Space Agency (ESA) and the Dutch Scientific Organisation (NWO).
2007-2012Continued grant (MG-057) from NWO-ALW via SRON/NSO for the Dutch Experiment Support Center, DESC.
2002-2007Continued grant from NWO-ALW via SRON for the Dutch Experiment Support Center, DESC
1999-2002Initiation of the Dutch Experiment Support Center, DESC. DESC initiates the science involvement in acceleration research, mainly in the area of life sciences. DESC provides access and support for ground-based facilities such as various centrifuges for hypergravity studies as well as apparatuses for microgravity simulations. DESC will also be involved in laboratory studies for new space hardware developments, support science proposal in the field of microgravity and space flight as well as conducting own research. The grant is provided by Dutch National Institute for Space Research (SRON) external programs as part of NWO-ALW.
1998-1999Guest employee at the Academic Center for Dentistry in Amsterdam (ACTA) Dept. of Cell Biology at the Free University in Amsterdam.
1994-1998Transition to full time employment at Bradford Engineering, Putte, The Netherlands. Involvement in developments for Biological and Material Science Gloveboxes, Biological Research facilities (BioPack), Experiment Containers (ECS), and other microgravity research payloads for the Space Shuttle, Mir and the International Space Station Alpha.
1993Part-time contract as logistics engineer for the European Space Agency, ESA’s, Biorack for the Shuttle IML-2 EST, Toulouse, France.
1988-1993Ph.D. student at the VU University Amsterdam, department of Oral Cell Biology. In this research project I studied the influence of various mechanical forces on bone cell growth, metabolism and structure. Main tasks were the preparation of two microgravity experiments (IML-1, Bion-10). During this period some time was dedicated to teaching general histology to dentist students and teaching cell culture techniques to medical Ph.D. students. 
1986-1988Technician at the VU University Amsterdam, Department of Oral Cell Biology, Amsterdam, The Netherlands.
1984-1985Teacher of laboratory practice and techniques, histology, light and electron microscopy at the Dr. Struycken Institute, Etten-Leur, The Netherlands.
1983-1984Technician at the pathology laboratory of the Ignatius Hospital, Breda, The Netherlands.

Selected scientific publications

Loesberg WA, Walboomers XF, Bronkhorst EM, van Loon JJ, Jansen JA.
The effect of combined simulated microgravity and microgrooved surface topography on fibroblasts. Cell Motil Cytoskeleton. 2007 Mar;64(3):174-85.
RG Bacabac, TH Smit, JJWA Van Loon, B Zandieh Doulabi, MN Helder, J Klein-Nulend.
Bone cell responses to high-frequency vibration stress: Does the nucleus oscillate within the cytoplasm? FASEB J. 2006 May; 20(7):858-64.
van Loon Jack J. W. A., Erik H. T. E. Folgering, Carlijn V. C. Bouten, J. Paul Veldhuijzen, and Theo H. Smit.
Inertial Shear Forces and the Use of Centrifuges in Gravity Research. What is the Proper Control? of ASME Journal of Biomechanical Engineering, 125(3), 342-46, June 2003.
Tristan F. B. Kraft, Jack J. W. A. van Loon, John Z. Kiss.
Plastid position in Arabidopsis columella cells is similar in microgravity and on a random-positioning machine. Planta 211(3), 415-422, 2000.
Jack J.W.A. van Loon, Dirk-Jan Bervoets, Elisabeth H. Burger, Suzanne C. Dieudonne, Jan-Willem Hagen, Cor M. Semeins, Behrouz Zandieh Doulabi and J. Paul Veldhuijzen.
Decreased mineralization and increased Calcium release in isolated fetal mouse long bones under near weightlessness. Journal of Bone and Mineral Research (JBMR), 10(4), 1995.

LIST OF PUBLICATIONS (from 1999 until now)